LLNL Computing’s ground-breaking research and development activities, innovative technologies, and world-class staff are often featured in various media outlets.
Source: LLNL Computing
A look back: “Cray Blitz” and the world of computer chess
The LLNL Archives reveal a surprising history of computing chess innovation and competition.
Careers Community Emerging Architectures HPC Architectures HPC Systems and Software Performance, Portability, and Productivity
Source: LLNL Computing
IPDPS 2026 acceptances
LLNL participates in the International Parallel and Distributed Processing Symposium (IPDPS) on May 25–29.
AI/ML Data Compression Data Science Emerging Architectures Events HPC Architectures HPC Systems and Software Quantum Computing Storage, File Systems, and I/O
Source: LLNL Computing
CASC Newsletter | Vol 17 | May 2026
Highlights include turbulent flows, virtual reality, correctness checkers, and AI for chemistry.
AI/ML Biology/Biomedicine Collaborations Computational Math Computational Science Data Science HPC Systems and Software Materials and Manufacturing ML Theory Natural Language Processing PDE Methods Programming Languages and Models Scientific ML UQ and Statistics
Source: LLNL News
Big Ideas Lab podcast spotlights how Skyfall defends the power grid from cyberattacks
The Skyfall laboratory is a hardware-in-the-loop testbed at LLNL where scientists simulate how real-world equipment will respond under stress.
AI/ML Critical Infrastructure Cyber Incident Response Cyber Research Cyber Security Data Science Multimedia
Source: LLNL Computing
NLIT 2026 event calendar
LLNL staff are heading to the National Laboratories Information Technology Summit (NLIT) on May 4–7.
Access Management AI/ML Cloud Services Collaboration and Productivity Tools Cyber Operations Cyber Security Data Management Data Science Databases/IT Infrastructure Events HPC Systems and Software Information Technology Network Engineering Software Build and Installation
Source: LLNL News
LLNL to harness quantum computing for next-generation magnets
The Quantum Computing for Computational Chemistry (QC3) program seeks to develop and apply quantum algorithms to accelerate simulations of chemistry and materials science to advance commercial energy applications.
AI/ML Data Science Emerging Architectures Information Technology Materials and Manufacturing Quantum Computing
Source: LLNL News
Big Ideas Lab podcast highlights HPC4EI
The Big Ideas Lab dives into the High Performance Computing for Energy Innovation program, a collaboration between national labs and private industry that tackles complex industrial challenges with computational science.
Computational Science Critical Infrastructure HPC Systems and Software Materials and Manufacturing Multimedia
Source: LLNL Computing
ICLR26 acceptances
LLNL researchers have several posters and papers accepted to the 13th International Conference on Learning Representations on April 23–27.
AI/ML Data Science Deep Learning Events ML Theory Natural Language Processing Scientific ML
Source: LLNL News
LLNL-led study uses machine learning, veterans’ health records to identify ALS drug-repurposing candidate
By combining causal-inference methods with machine learning, researchers evaluated 162 medications to identify drugs prescribed for other conditions that were associated with meaningful differences in survival.
Source: LLNL Computing
Better solvers, better precision with HYPRE v3
The latest chapter in the nearly 30-year history of hypre includes a new semi-structured algebraic multigrid solver and support for mixed numerical precision at runtime.
Source: The Innovation Platform
Livermore Computing: accelerating excellence in high performance computing
To learn more about the work taking place at Livermore Computing and the potential this has for a wide range of real-world applications, The Innovation Platform spoke to LLNL’s Deputy for High Performance Computing, Judy Hill.
AI/ML Data Science Emerging Architectures HPC Architectures HPC Systems and Software Hybrid/Heterogeneous Open-Source Software
Source: LLNL News
LLNL, Meta co-develop groundbreaking polymer-chemistry dataset for training AI models
In a pioneering partnership to accelerate materials discovery with AI, researchers from LLNL and Meta have created the world’s largest open dataset of atomistic polymer chemistry.
AI/ML Computational Science Data Management Data Science Materials and Manufacturing
Source: LLNL Computing
Supercomputer allocations boost HPC-LLM project
An LLNL-led team is using 700,000 node-hours of Department of Energy HPC resources to improve developer productivity.
AI/ML Data Science Exascale HPC Architectures HPC Systems and Software Natural Language Processing Performance, Portability, and Productivity Software Engineering
Source: LLNL News
HPC4Mfg program awards funding to three LLNL-industry collaborations
The HPC for Manufacturing program is part of the broader HPC4EI initiative, which LLNL manages for DOE. HPC4Mfg connects U.S. companies with national lab expertise and computing resources to address complex manufacturing challenges using advanced modeling and simulation.
Collaborations Computational Science Materials and Manufacturing Transport
Source: LLNL News
Finding resonance: How LLNL expertise is amplifying collaboration in quantum computing
A DOE investment unites experts from national labs, universities, and industry to advance the next generation of quantum computing, communication, and sensing technologies. LLNL brings a deep expertise in materials and microwave cavities to the table.
Source: LLNL Computing
SIAM PP26 event calendar
Our researchers will be well represented at the SIAM Conference on Parallel Processing for Scientific Computing (PP26) on March 3–6. SIAM is the Society for Industrial and Applied Mathematics with an international community of more than 14,000 individual members.
AI/ML Biology/Biomedicine Co-Design Compiler Technology Computational Math Computational Science Data Science Discrete Mathematics Emerging Architectures Exascale HPC Systems and Software PDE Methods Quantum Computing Seismology Solvers
Source: Science & Technology Review
Supercomputing in sync
The National Nuclear Security Administration’s high performance computing environments rely on a unified, scalable operating system.
Cluster Management HPC Architectures HPC Systems and Software Hybrid/Heterogeneous
Source: LLNL News
Fentanyl or phony? ML algorithm learns to pick out opioid signatures
LLNL scientists initiated and led a cross-disciplinary team that developed a machine learning model to distinguish opioids from other chemicals.
Source: LLNL News
Simulations and supercomputing calculate one million orbits in cislunar space
In an open-access database and with publicly available code, LLNL researchers have simulated and published one million orbits in cislunar space.
Source: LLNL News
LLNL makes Glassdoor’s 2026 ‘Best Places to Work’ list
The Lab ranked 12th out of 100 large employers in the United States, marking the seventh recognition the Laboratory has earned in Glassdoor’s award program since its inception in 2009.
Source: LLNL News
LLNL’s Lindstrom honored with IEEE VIS Test of Time Award
Computer scientist Peter Lindstrom received the 2025 IEEE VIS Test of Time Award for his 2014 paper on near-lossless data compression, recognizing its lasting influence on the field of scientific visualization and HPC.
Awards Data Compression Data Movement and Memory Data Science HPC Systems and Software Scientific Visualization
Source: Data Science Institute
AI in eight pages: Bridging technology to policy through science
LLNL, in collaboration with the California Foundation for Commerce and Livermore Lab Foundation, has released a new report to help California lawmakers navigate the fast-moving AI landscape.
Source: LLNL Computing
Livermore hosts HPSS User Forum for the first time in 33 years
In early November, Lawrence Livermore National Laboratory hosted the High Performance Storage System (HPSS) User Forum, marking the first time in the collaboration’s 33-year history the global HPSS user community gathered in Livermore.
Collaborations Data Movement and Memory Developer Support Events Storage, File Systems, and I/O
Source: LLNL Computing
Computing advances highlighted at DOE’s SC25 exhibit booth
During the weeklong conference, attendees visiting the Department of Energy’s booth were treated to two technical demonstrations and a talk by LLNL staff.
AI/ML Algorithms at Scale Biology/Biomedicine Computational Science Containerization Data Science Events Exascale HPC Systems and Software Lasers and Optics Natural Language Processing Resource and Workflow Management Scientific ML
Source: YouTube
Video: How supercomputers are transforming research in cancer, dark matter, and seismology
Researchers are using LLNL’s unclassified supercomputers to delve into complex scientific questions such as uncovering how protein interactions are linked to cancer, shedding light on mysterious dark matter, and understanding the shifting dynamics of seismic waves.
Biology/Biomedicine Collaborations Computational Science HPC Systems and Software Multimedia Seismology Space Science
Source: YouTube
Video: 2025 LLNL highlights
In 2025, LLNL built on our legacy of groundbreaking scientific and technological innovation with the help of partners from throughout the federal government, nuclear security enterprise, the national laboratory system, industry, and academia.
Source: LLNL Computing
CASC Newsletter | Vol 16 | December 2025
Highlights include innovative solutions for contact mechanics, HPC optimization, quantum dynamics, and carbon capture.
Compiler Technology Computational Math Computational Science Data Science Data-Driven Decisions Discrete Mathematics Earth Systems Emerging Architectures HPC Systems and Software Hybrid/Heterogeneous Materials and Manufacturing Mathematical Optimization Open-Source Software PDE Methods Performance, Portability, and Productivity Programming Languages and Models Quantum Computing Software Engineering Solvers
Source: LLNL News
LLNL caps SC25 with HPC leadership, major science advances and artificial intelligence
LLNL’s presence, which included dozens of sessions, including tutorials, workshops, paper presentations and birds-of-a-feather meetings was felt across virtually every major event of the week.
AI/ML Awards Community Computational Math Computational Science Data Science Events Exascale HPC Systems and Software Scientific ML
Source: YouTube
Video: The perfect metaphor for AI security
How do we keep artificial intelligence safe and secure as it advances at breakneck speed? This video explores the risks of AI systems powering today’s chatbots, virtual assistants, and more.
Source: LLNL Computing
LLNL honored at SC25 with HPCwire and Hyperion Research awards for computing excellence
At SC25, LLNL earned multiple top honors across exascale computing, open-source software and real-world scientific applications, receiving four 2025 HPCwire awards and a Hyperion Research HPC Innovation Excellence Award.
Source: LLNL Computing
Early-career researchers provide insight into power grid optimization at annual FERC conference
Four Laboratory early-career researchers presented their work at this year’s Federal Energy Regulatory Commission conference.
Critical Infrastructure Events Mathematical Optimization UQ and Statistics
Source: LLNL Computing
NeurIPS 2025 acceptances
Join LLNL at the 39th annual Conference on Neural Information Processing Systems on December 2–7.
Source: LLNL News
LLNL, UT & UCSD win Gordon Bell Prize with exascale tsunami forecasting
Widely viewed as the highest recognition in HPC, the Gordon Bell Prize recognizes innovations that push the limits of computational performance, scalability and scientific impact on pressing real-world problems.
Algorithms at Scale Awards Collaborations Computational Math Computational Science Exascale HPC Systems and Software PDE Methods
Source: LLNL News
Gordon Bell finalist team pushes scale of rocket simulation on El Capitan
Researchers used the exascale supercomputer El Capitan to perform the largest fluid dynamics simulation ever—surpassing one quadrillion degrees of freedom in a single computational fluid dynamics problem.
Algorithms at Scale Computational Science Exascale HPC Systems and Software Hydrodynamics
Source: LLNL News
El Capitan retains title as world’s fastest supercomputer on latest Top500 list
El Capitan once again claimed the top spot on the Top500 List of the world’s most powerful supercomputers, announced today at the 2025 International Conference for High Performance Computing, Networking, Storage and Analysis (SC25) conference in St. Louis.
Awards Emerging Architectures Exascale HPC Architectures HPC Systems and Software
Source: LLNL News
LLNL and partners launch record-breaking protein-folding workflow on world’s fastest supercomputer
Scientists at LLNL and collaborators at AMD and Columbia University have achieved a milestone in biological computing: completing the largest and fastest protein structure prediction workflow ever run, using the full power of El Capitan.
AI/ML Biology/Biomedicine Computational Science Data Science Exascale Scientific ML
Source: LLNL Computing
SC25 event calendar
LLNL is participating in the 37th annual International Conference for High Performance Computing, Networking, Storage, and Analysis (SC25) in St. Louis on November 16–21, 2025.
AI/ML Awards Careers Collaborations Computational Math Computational Science Data Compression Data Movement and Memory Data Science Debugging and Correctness Emerging Architectures Events Exascale HPC Architectures HPC Systems and Software Open-Source Software Outreach Performance, Portability, and Productivity Programming Languages and Models Quantum Computing Resource and Workflow Management Scientific Cloud Computing Scientific ML Software Build and Installation
Source: LLNL Computing
Workshop features finite element advances and applications
Five years strong, the MFEM workshop fosters connection and collaboration among the computational math community.
Computational Math Computational Science Discrete Mathematics Events Exascale HPC Systems and Software Open-Source Software PDE Methods Software Libraries
Source: Data Science Institute
ParaView-MCP levels the playing field for complex scientific visualization
A new study led by CASC researchers empowers users to interact with the application through natural-language and visual inputs instead of the typical graphic user interface, which can appear daunting for novice users.
AI/ML Data Science Natural Language Processing Scientific Visualization
Source: LLNL News
LLNL ranked among Glassdoor’s Best-Led Companies of 2025
LLNL has been recognized for the second year as one of Glassdoor’s Best-Led Companies in the United States, earning the No. 32 spot out of 50 on the 2025 list.
Source: Science & Technology Review
S&TR cover story: Supercomputing rises to grand scientific challenges
The latest issue of LLNL's magazine marks the 20th anniversary of the Computing Grand Challenge.
Biology/Biomedicine Collaborations Computational Science HPC Systems and Software Seismology Space Science
Source: LLNL News
El Capitan revealing hidden worlds in previously unattainable high-fidelity simulations
From capturing the chaotic spray of molten metal to the turbulence of fluid flows, the exascale machine is revealing worlds that were previously beyond reach, and it’s doing so thanks to the close collaboration of hardware, software and science teams that makes LLNL uniquely equipped to lead in this space.
Computational Science Emerging Architectures Exascale HPC Systems and Software Hydrodynamics Lasers and Optics
Source: LLNL News
LLNL used AI to predict historic fusion ignition shot
LLNL researchers employed an AI-driven model to predict fusion ignition days ahead of the historic 2022 shot, according to a new study in Science.
AI/ML Computational Science Data Science Lasers and Optics Scientific ML
Source: Science & Technology Review
Cracking the fusion codes
LLNL is home to the world’s most complete set of ICF modeling and simulation tools, encapsulating the intricacies of laser light interaction, electron and x-ray transport, nonequilibrium atomic physics, magnetohydrodynamics, and fusion burn.
Computational Science HPC Systems and Software Hydrodynamics Lasers and Optics
Source: LLNL News
LLNL scientists explore real-time tsunami warning system on world’s fastest supercomputer
Scientists at LLNL have helped develop an advanced, real-time tsunami forecasting system—powered by El Capitan, the world’s fastest supercomputer—that could dramatically improve early warning capabilities for coastal communities near earthquake zones.
Computational Math Computational Science Discrete Mathematics Exascale HPC Architectures Open-Source Software PDE Methods
Source: LLNL News
Big ideas, big milestone: Lab podcast surpasses one million downloads
Launched in Sept. 2024, the podcast set out to offer a fresh perspective on science communication, bringing researchers, innovators, and thought leaders together for conversations about the ideas shaping the future.
Source: LLNL News
LLNL pushes frontier of fusion target design with AI
Part of an AI framework called the Multi-Agent Design Assistant (MADA), LLNL scientists and collaborators are merging LLMs with simulation tools to interpret natural language prompts and using the platform to generate full physics simulation decks for LLNL’s MARBL multiphysics code.
Source: LLNL Computing
Shifting foundations: an AI paradigm emerges in computational science
A new CASC paper proposes unity and clarity around foundation models in computational science, offering an implementation framework inspired by finite element methods.
AI/ML Collaborations Computational Math Computational Science Data Science Discrete Mathematics ML Theory Scientific ML
Source: LLNL News
Lori Diachin named to 2025 ‘legends’ of HPC list
LLNL’s Principal Deputy for Computing Lori Diachin has been named one of HPCwire’s “35 Legends” for 2025, a recognition that celebrates pioneers, visionaries and champions who have left an enduring mark on HPC.
Source: Brown University
Faster topology optimization: an emerging industrial design technique gets a speed boost
Researchers at Brown University, LLNL, and Simula Research Laboratory have developed a new algorithm to help optimizers arrive at solutions in fewer iterations, saving valuable computing time.
Collaborations Computational Math Computational Science Materials and Manufacturing Mathematical Optimization
Source: Science & Technology Review
S&TR cover story: Another innovation celebration
A unique laser optic design and two novel open-source software projects bring the Laboratory’s R&D 100 awards total to 182.
Awards Data Movement and Memory Emerging Architectures HPC Systems and Software Lasers and Optics Near Memory Computing Open-Source Software Storage, File Systems, and I/O
Source: LLNL Computing
ICML25 acceptances
LLNL researchers have posters and workshop papers accepted to the 42nd International Conference on Machine Learning on July 13–19.
AI/ML Computational Math Data Science Events ML Theory Scientific ML UQ and Statistics
Source: LLNL Computing
Robust evaluation of PDE solutions on high-order meshes
A new mathematical technique improves the computational efficiency of evaluating the solution in large-scale, high-order meshes on advanced HPC systems.
Computational Math Discrete Mathematics HPC Systems and Software Hybrid/Heterogeneous PDE Methods Programming Languages and Models
Source: LLNL News
Cancer drug candidate developed using supercomputing & AI blocks tumor growth without toxic side effect
A new cancer drug candidate developed by LLNL, BridgeBio Oncology Therapeutics, and the Frederick National Laboratory for Cancer Research has demonstrated the ability to block tumor growth without triggering a common and debilitating side effect.
AI/ML Biology/Biomedicine Collaborations Computational Science Data Science Scientific ML
Source: LLNL Computing
Global community convenes for Spack’s first user meeting
Nicknamed SUM25, Spack’s first user meeting showcased new development and a thriving community.
Events HPC Systems and Software Open-Source Software Outreach Software Build and Installation
Source: LLNL News
El Capitan reigns supreme across three major supercomputing benchmarks
LLNL's flagship exascale machine maintained its status as the fastest supercomputer on the planet—claiming the No. 1 spot on not just one, but three of the most prestigious HPC rankings.
Source: LLNL News
LLNL Deputy Director Pat Falcone receives inaugural AI Honors in Public Science Award
Organizers praised Falcone's “extraordinary leadership in driving research directions to advance science and technology at one of America's most vital research institutions.”
Source: Science & Technology Review
S&TR highlight: AI leadership for national security
As the application of AI across industries accelerates the pace of development, so too must national security remain at the cutting edge, a task requiring extensive collaboration to deploy the nation’s most critical resources.
Source: High Performance Computing Innovation Center
Register for HPC tutorials this summer
Learn how to use a modern, open-source HPC software stack! From mid-July to mid-September, join our tutorials on how to install and use several projects on AWS EC2 instances (provided). All experience levels are welcome.
Education Events HPC Systems and Software Open-Source Software Outreach Scientific Cloud Computing Software Engineering Software Libraries
Source: LLNL News
LLNL, Amazon partner on groundbreaking AI integration at the National Ignition Facility
LLNL and Amazon Web Services are partnering to leverage the power of AI to enhance operations at the National Ignition Facility.
AI/ML Computational Science Data Management Data Science Lasers and Optics Natural Language Processing
Source: LLNL News
Stanford professor discusses future of visually intelligent machines and human-AI collaboration
Stanford University professor and AI visionary Fei-Fei Li went beyond technical milestones from her two-decade career into her philosophy of intelligence, ranging from the evolution of vision in the Cambrian Age to modern-day “robot cousins” that can see and assist humans in everyday menial tasks.
Source: LLNL News
Big Ideas Lab podcast enters the quantum realm
In the current episode of the Big Ideas Lab, dive into the strange new frontier where physics meets information, and reality gets rewritten—qubit by qubit.
Source: LLNL News
LLNL researchers use AI to look for potential ALS treatments
A team of researchers from LLNL, Stanford University, and UCLA are using AI and machine learning to find potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases in the form of drugs prescribed for other conditions.
Source: LLNL Computing
ISC25 event calendar
LLNL participates in the ISC High Performance Conference (ISC25) on June 10–13.
AI/ML Data Science Emerging Architectures Events HPC Systems and Software Hybrid/Heterogeneous Natural Language Processing Performance, Portability, and Productivity Programming Languages and Models Resource and Workflow Management Scientific Cloud Computing Scientific ML Software Build and Installation
Source: LLNL News
DOE Secretary Wright gets up-close look at innovation in action during LLNL visit
Wright’s day-long visit—his first to LLNL since being appointed Energy secretary—included behind-the-scenes tours of some of LLNL’s most advanced facilities and machines, from the National Ignition Facility to El Capitan, the world’s most powerful supercomputer.
Source: LLNL News
U.S. Energy Secretary Wright visits LLNL
Wright’s daylong visit included briefings and discussions with LLNL experts in key mission areas including stockpile modernization, fusion energy, AI, cyber security and supercomputing.
AI/ML Cyber Security Data Science Events HPC Systems and Software
Source: LLNL News
Big Ideas Lab podcast examines how AI Is reshaping science at LLNL
On the latest episode of The Big Ideas Lab podcast, listeners will get an inside look at this transformation, as LLNL physicists Brian Spears and Kelli Humbird explain how AI is no longer just about chatbots and automating simple tasks.
Source: LLNL Computing
Proteus arrives just in time for faster HPC code compilation
A new just-in-time compilation approach leverages LLVM intermediate representation to optimize GPU kernels with portability to any GPU architecture.
Compiler Technology HPC Systems and Software Hybrid/Heterogeneous Open-Source Software Performance, Portability, and Productivity Programming Languages and Models
Source: LLNL News
‘STEM Day at the Lab’ enters its 10th year of bringing science to LLNL communities
LLNL STEM Day ignites curiosity and shapes futures, delivering high-quality science, technology, engineering and math (STEM) education to more than 1,935 students—and the impact keeps growing.
Source: LLNL Computing
Distinguished paper offers unique solution for GPU offloading
Research recognized at the HiPC IEEE conference proposes using an optimized version of OpenMP for vendor-agnostic GPU performance, portability, and scalability.
Compiler Technology Data Movement and Memory HPC Architectures HPC Systems and Software Hybrid/Heterogeneous Middleware Performance, Portability, and Productivity Programming Languages and Models Software Engineering
Source: LLNL News
Dream Day inspires Livermore students to explore STEM careers
More than 50 students from five Livermore middle schools visited LLNL on April 18 for Dream Day, an event filled with hands-on science, technology, engineering and mathematics (STEM) activities.
Source: LLNL News
Simulating hot-spot formation in insensitive high explosives
Using the Sierra supercomputer, an LLNL team has made significant progress in understanding how microscopic hot spots form in insensitive high explosives based on TATB.
Source: LLNL Computing
ICLR25 acceptances
LLNL researchers have posters and workshop papers accepted to the 13th International Conference on Learning Representations on April 24–28.
AI/ML Data Science Deep Learning Events ML Theory Natural Language Processing Scientific ML
Source: LLNL News
New nucleotide database could improve microbe identification for science and medicine
LLNL researchers have created new, optimized indices of the nt database that simplify how scientists classify microorganisms found in various samples, significantly improving the ability to identify and understand the myriad microorganisms that inhabit our world.
Bioinformatics Data Management Data Science Databases/IT Infrastructure Information Technology
Source: LLNL News
LLNL scientists use AI to optimize antibodies against mutations and accelerate pandemic preparedness
Researchers from LLNL, in collaboration with other leading institutions, have successfully used an AI-driven platform to preemptively optimize an antibody to neutralize SARS-CoV-2 variants.
AI/ML Biology/Biomedicine Collaborations Computational Science Data Science Scientific ML